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Families with kids of all ages will love this mountain village, located just two hours from Panama City. Whether you’re up for active sports such as hiking, biking, horseback riding and ziplining through the rainforest—or sightseeing adventures such as the El Nispero Zoo and Serpentario (a snake habitat), you’ll find it here. El Valle de Antón is home to the world’s second-largest extinct volcano—but you’ll still find more modern pleasures here, such as its well-known Sunday Market and elegant spas such as Casa de Lourdes.